⚡️WHAT IS CAFFEINE?⁣
1,3,7-Trimethylxanthine also known as caffeine is a naturally-occurring stimulant substance of the xanthine class. Notable effects include stimulation, wakefulness, enhanced focus and motivation. It is the most widely consumed psychoactive substance in the world (Pyschonaut Wiki, 2019).⁣
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👨🏻‍🔬HOW CAFFEINE AFFECTS THE BRAIN:⁣
Caffeine is known to influence a variety of neurotransmitters, including dopamine, acetylcholine, serotonin, and, in high doses, on norepinephrine, and to a small extent epinephrine, glutamate, and cortisol. At high doses, exceeding 500 milligrams, caffeine inhibits GABA neurotransmission. GABA reduction explains why caffeine increases anxiety, insomnia, rapid heart and respiration rate at high dosages (Jones et al., 2006).⁣
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❌UNDERSTANDING WITHDRAWALS:⁣
Chronic caffeine intake can lead to upregulation of adenosine A2A receptors, which is accompanied by sensitization. This may explain why people experience BRAIN FOG, fatigue and sleepiness without their caffeine (Varani et al., 1999). ⁣
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💥TAKEAWAY:⁣
Caffeine withdrawal affects the brain in a myriad of ways. There are certainly ways to improve energy/mental clarity without caffeine, and I will be exploring these in future posts. DM me for more info in the mean time. ⁣
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💡DO YOU EXPERIENCE WITHDRAWALS? COMMENT BELOW. ⁣
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✭ Ergogenichealth.com.au⁣
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